Analyst Insight: For the better part of 40 years truly leading-edge firms have made supply chain design/redesign using network optimization models an integral part of their overall corporate strategy. The focus has gradually evolved from a myopic consideration of the number and location of warehouses to a comprehensive examination of the entire supply chain, from sources of raw materials to the customer. The principal impediments to success are myopic scope and failure to institutionalize the process. - Jeffrey J. Karrenbauer, President, Insight Inc.